Reduced tumor-producing capacity of mycoplasma-modified lines of FL human amnion cells in the cheek pouch of cortisonized hamsters.

Spontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

Heightened Immunity and Susceptibility toward Cheek Pouch Heterografts of a Mouse Leukemia in Syrian Hamsters.

Heterotransplantation of 1.0 X IO7AK-4 cells of AKR mice into cheek pouches of normal and cortisone-treated adult Syrian hamsters resulted in measurable but tran sient growth; small vascular tumors which appeared at 5-7 days regressed completely by 10-14 days. Noncortisonized hamsters vigorously rejected second-set grafts, which failed to vascularize, in considerably less time, in either the pr...

Blood cell factors and tumor growth in the cheek pouch of the golden hamster (Mesocricetus auratus).

Modification of the immunologic response to human choriocarcinoma in the hamster cheek pouch by heterologous antilymphocyte serum.

Because the immune response to human choriocarcinoma growing in the hamster cheek pouch makes it difficult to evaluate the responsiveness of the tumor to drugs, we have studied this immune response in untreated hamsters and hamsters immunologically suppressed with heterologous antilymphocyte serum (ALS). Untreated animals were immunized by the tumor beginning as early as 6 days after implantati...

The WIRL-3 rat liver cell lines and their transformed derivatives.

the characteristics associated with hepatocytes. They have glucose 6-phosphatase activity, secrete serum globulin, and, in confluent monolayers, show tight cell junctions and intercellular canaliculi resembling bile canaliculi. On the other hand, the cells have low levels of inducible tyrosine aminotransferase, no detectable 6-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase acti...